Sweating is a very normal human response and it happens as our body works to keep us from overheating, particularly in the heat and during exercise. Some of us sweat more than others, and when the sweat response is excessive and uncontrollable, it’s referred to as primary hyperhidrosis. It commonly involves the underarms, palms, and soles and can cause stress for the individual due to social stigmatization (1). Successful and long term treatments are lacking when it comes to excessive sweating. This week I explain how Botox can be used to manage excessive underarm sweating.