Methylene Blue for Memory
Over the past six weeks or so, my friend Dr. Okojie and I have been getting together each week to trade IV therapy treatments. I was introduced to methylene blue (MB) during one of these treatments, and have had four or so infusions ever since. I didn’t know much about this substance and the color was awfully reminiscent of toilet bowl cleaner. I trust Dr. Okojie and his work so I was willing to try. After experimenting and researching on MB, I decided to add this service because of its anti-aging properties. This week I share the benefits of MB and show how you can incorporate this into your self-care regimen.
MB is a medication and blue dye that was FDA approved for its treatment of a specific anemia. MB has become popular as of late for its effect on the cell’s mitochondria. Most cells in our body have multiple mitochondria, AKA the cell’s powerhouse, because this is where energy is made. Most of our food is broken down into glucose by the body. Glucose byproducts enter the mitochondria and electron transport chain. The electron transport chain transports electrons down a chain and at the end of the chain, oxygen releases energy to make ATP. ATP is energy, and ATP is required for our body to function.
As we age, our mitochondria decline in its ability to function (1). It is established that the mitochondria play a key role in regulating brain function and cognition in aging (2). Memory loss may be a symptom of inefficient mitochondrial function. Essentially, the electrons are not being transported as efficiently and the amount of oxygen available to make ATP is reduced. Enter MB. MB acts as an electron donor and can help donate these electrons so the chain is complete and energy is produced. It also helps the brain use oxygen more efficiently and when dosed appropriately, facilitates memory retention (3). At low doses, MB enhances mitochondrial energy production, is an antioxidant, and improves memory (4).
MB protects the nervous system by promoting mitochondrial electron transfer chain function (5). MB has been shown to repair some neurological impairments in Alzheimer’s disease. Further, MB showed to positively influence neurotransmitter systems which are believed to play a role in Alzheimer’s and other cognitive disorders.
MB is safe to take at low doses (<2ml/kg), but not safe at high doses. If you are interested in trying MB for its neuroprotection and memory enhancing properties, I have formulated a three month program that consists of weekly methylene blue IV treatments for one month, supported by daily oral dosing. Feel free to schedule a virtual consult or email me with interest.
Resources
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003832/
https://pubmed.ncbi.nlm.nih.gov/21454572/